ZeroGov

The pharmacokinetics of cyclizine in pregnant women

Cyclizine is an antihistamine and anticholinergic agent with strong sedative properties. It is used to treat nausea, vomiting and vertigo. Cyclizine crosses the blood-brain barrier and its main site of action is the central nervous system.

Very little is known about the pharmacokinetics of cyclizine in pregnant women. A study in pregnant rats found that cyclizine crosses the placenta and is distributed into fetal tissues. The elimination half-life of cyclizine was prolonged in pregnant rats compared to non-pregnant rats.

It is not known if cyclizine is secreted in human milk. The manufacturer recommends that cyclizine be used with caution in nursing mothers.

Cyclizine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Animal studies have shown that cyclizine crosses the placenta and is distributed into fetal tissues. There are no adequate and well-controlled studies in pregnant women.

Nausea and vomiting are common complaints during pregnancy. If cyclizine is ineffective in treating these symptoms, other options include metoclopramide, ondansetron, and prochlorperazine..Find Out More

The long-term effects of cyclizine exposure during pregnancy

Cyclizine is an antihistamine that is used to treat nausea, vomiting, and dizziness. It is marketed under the brand names Marezine and Cyclizine Hydrochloride. Cyclizine is classified as a pregnancy category B drug by the US Food and Drug Administration (FDA). This means that it is not expected to be harmful to an unborn baby. However, there is no adequate data on the use of cyclizine in pregnant women. Animal studies have not shown any adverse effects on the fetus, but there is no reliable data on the effects of cyclizine in human pregnancy. The manufacturer recommends that cyclizine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Pregnant women should be advised to avoid lengthy exposure to sunlight or artificial ultraviolet rays while taking cyclizine. There is a potential for the drug to increase the skin’s sensitivity to sunlight. This could lead to sunburn, rashes, or other skin problems. It is also recommended that women who are pregnant or breastfeeding should avoid alcohol while taking cyclizine.

Cyclizine has been detected in human milk. The manufacturer recommends that caution should be exercised when cyclizine is administered to a nursing woman.

There are no well-controlled studies on the use of cyclizine in pregnant women. The manufacturer recommends that cyclizine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Pregnant women should be advised to avoid lengthy exposure to sunlight or artificial ultraviolet rays while taking cyclizine. Cyclizine has been detected in human milk and caution should be exercised when cyclizine is administered to a nursing woman.

Visit pregnancysicknesssuport.org.uk to learn more about cyclizine when pregnant. Disclaimer: We used this website as a reference for this blog post.